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5–4 μmol/L vary,[156][157] the focus of serotonin in synaptic vesicles was calculated at 270 mM.[182] pursuing vesicular release, the resulting concentration of serotonin while in the synaptic cleft, to which serotonin receptors are uncovered, is believed to be about three hundred μmol/L. So, even though in vitro receptor binding affinities,

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